The RNA Self Containment Web Server calculates the Self-Containment Index (SC), as described in Lee and Kim (2008). It measures the robustness of RNA substructures to changes in their surrounding sequence context, which we hypothesize to be a hallmark of structural modularity. SC values range from 0.0 (no self containment) to 1.0 (completely self contained). For a full description and to download an offline version, please visit the Kim Laboratory Software Repository and refer to our paper in PLoS Comp Biol.

Paste or type your RNA sequence here (maximum 300 nucleotides): [?]

Number of random contexts to use: [?]

100 (fastest) 200 500 (more accurate)

Length of each random context: [?]

0.5 * input length (faster) 1.0 * input length


If you find this service useful, please cite: M.T. Lee and J. Kim. 2008. 'Self Containment, a Property of Modular RNA Structures, Distinguishes microRNAs.' PLoS Comp. Biol. 4(8):e1000150 doi:10.1371/journal.pcbi.1000150